How Is Marijuana Metabolized?
The first question you might have is: How is marijuana metabolized? THC is absorbed directly into the blood and the brain, but it goes through a process of metabolism before reaching the bloodstream. This metabolism begins in the gastrointestinal tract and continues in the liver. The result is metabolites that are marked for excretion out of the body. THC is broken down into its various constituent parts and then excreted. can someone who’s been convicted have a medical marijuana card in ny
THC is metabolized in the liver through oxidation and microsomal hydroxylation. These processes involve the action of CYP complex enzymes. When marijuana is metabolized, approximately 65% is excreted through urine and 20% is excreted through feces. However, the absorption rate of CBD varies depending on the way it is consumed. It is metabolized, but it is not well absorbed. Most of the CBD is excreted in the feces.
A third major step in understanding how marijuana is metabolized is identifying the amount of THC in urine. The liver can detect THC, which is a component of marijuana, when a person consumes it. There is no specific test that can distinguish between oral and smoked cannabis, but there are some differences. Using marijuana while breastfeeding will result in higher levels of THC than when the drug is ingested orally. Similarly, the amount of THC in a urine test will be four to seven times lower than if the drug is smoked. Passive inhalation will not lead to a positive test.
The liver metabolizes THC into a variety of metabolites. The metabolite 11-OH-THC is particularly potent. The body converts less than 20% of THC to 11-OH-THC when smoked or consumed in edible forms. In contrast, only 20% of inhaled THC is converted to 11-OH-THC on the first pass through the liver. As such, marijuana is eliminated much faster after ingested than when smoked.
As a result, studying how cannabis is metabolized can help researchers identify which pathways are most likely to affect a person’s health in the real world. Moreover, it may help scientists understand the general cross-talk between the two substances’ molecular structure. Once the body has metabolized THC, it passes on to the kidneys for final excretion. The body’s glucuronidation pathway facilitates excretion.
Although blood THC concentrations are relatively stable after ingested THC, they are difficult to interpret. The amount of THC ingested, the frequency of use, and the timing of urine collection relative to the last exposure to marijuana all determine the time that the metabolite is present in the urine. Further research is needed to determine how reliable this method is in determining when a person has been using marijuana.
Research has also shown that marijuana can alter the metabolism of food. Consuming marijuana can lead to a number of undesirable effects. For example, people who smoke marijuana regularly report suffering from nausea, sleep disturbances, and anxiety. Additionally, frequent marijuana users have smaller waistlines than non-users. In addition, marijuana has a positive effect on the hypothalamus, which is located in the brain. Regardless of the effects of marijuana, the research suggests that it will help inform the drug’s medical development.